American Journal of Obstetrics and Gynecology · 2007
PESSRI
Pessary Ring versus Gellhorn Study — Randomized Investigation

The PESSRI Study: Symptom Relief Outcomes of a Randomized Crossover Trial of the Ring and Gellhorn Pessaries

Cundiff GW, Amundsen CL, Bent AE, Coates KW, Schaffer JI, et al.
DOI: 10.1016/j.ajog.2007.02.018
Design
Crossover RCT
Enrolled
134
Sites
6
Per Pessary
3 months
Completed Both
~63%
Crossover Design
Each woman used both pessaries for 3 months each in random order, serving as her own control. Of 134 enrolled, 85 completed both arms. Data available: n=94 for ring with support, n=99 for Gellhorn.
Pessary A · n = 94 evaluable
Ring with Support
Ring pessary with support diaphragm
Pessary B · n = 99 evaluable
Gellhorn
Gellhorn pessary with concave disc and stem
Population
61 yrMean age
82%Postmenopausal
Stage IIIMedian POP-Q
51%Anterior
34%Apical
10%Posterior
Key Result
No Clinically Significant Difference Between Pessaries
Both ring with support and Gellhorn produced statistically and clinically significant improvements in PFDI and PFIQ symptom scales. Between-pessary comparisons showed no meaningful differences on any subscale.
Outcome Summary: Between-Pessary Comparisons
Scale Ring Improved? Gellhorn Improved? P (between) Difference
Pelvic Floor Distress Inventory (PFDI)
POPDI Yes Yes 0.99 NS
UDI Yes Yes 0.62 NS
CRADI Yes Yes 0.91 NS
Pelvic Floor Impact Questionnaire (PFIQ)
POPIQ 0.29 NS
UIQ 0.74 NS
CRAIQ 0.29 NS
Satisfaction Analysis
VAS satisfaction was bimodal. For the Gellhorn, high satisfaction (≥8/10) was associated with symptom improvement (ΔUDI P=.001, ΔPOPDI P=.001, ΔCRADI P=.012). For the ring with support, high satisfaction was not significantly associated with symptom improvement — driven instead by ease of use and comfort.
Fitting & Completion Data
8% could not be fitted with at least one pessary; 4% could not be fitted with either. Refitting required: 28% ring, 33% Gellhorn. Younger women and non-white women were less likely to complete the study.
Clinical Bottom Line

Ring with support and Gellhorn pessaries are equally effective for relieving POP symptoms — especially protrusion and voiding dysfunction. Clinician and patient preference should guide pessary type selection. The Gellhorn may provide more symptom-correlated satisfaction, while ring satisfaction is driven more by ease of use.