New England Journal of Medicine · 2007
SISTEr
Stress Incontinence Surgical Treatment Efficacy Trial

Burch Colposuspension versus Fascial Sling to Reduce Urinary Stress Incontinence

Albo ME, Richter HE, Brubaker L, Norton P, Kraus SR, et al. · Urinary Incontinence Treatment Network
DOI: 10.1056/NEJMoa070218 · NCT00064662
Design
RCT
Patients
655
Sites
9 US centers
Follow-up
2 years
Completion
79%
Randomized Arms
Arm A · n = 326
Fascial Sling
Autologous rectus fascia pubovaginal sling
Arm B · n = 329
Burch
Modified Burch colposuspension
Primary Outcome: Overall Success at 24 Months
47%
Sling Success
38%
Burch Success
P = 0.01
Favors Sling
Key Outcomes
Stress-Specific Success
Sling
66%
Burch
49%
P < 0.001
Surgical Retreatment
Sling
2%
Burch
11%
P < 0.001
Patient Satisfaction
Sling
86%
Burch
78%
P = 0.02
Differential Complications
Higher with Sling
Voiding dysfunction: 14% vs 2% (P < 0.001)
UTIs: 48% vs 32%
Urge incontinence Tx: 27% vs 20% (P = 0.04)
Higher with Burch
Incidental cystotomy: 10 vs 2
Ureteral injury: 2 vs 0
Retreatment rate: 11% vs 2%
Clinical Bottom Line

The autologous fascial sling is more effective than Burch colposuspension for stress incontinence (47% vs 38% overall; 66% vs 49% stress-specific) but carries higher morbidity — voiding dysfunction, UTIs, and urge incontinence. This trial predates midurethral synthetic slings and provides the benchmark against which newer procedures were compared.